Intaking too much progesterone pills can result in the change in the size and tenderness of the breasts and the menstrual cycle of a woman. It can also affect the digestive system of a woman, causing nausea, heartburn, stomach cramps, diarrhea, and vomiting. Mood is liable to change into depression, too. Women would undergo sleeping disorders and weight gain due to the excessive consumption of progesterone pills. In addition, the side effects can include dizziness, faintness, chest pain, blurred vision, double vision, dilated eyes, tingling or numbness in the hands and feet, vaginal bleeding, rapid heartbeat, headache, constipation, difficulty in breathing, uncontrollable shaking, swelling or pain in the face, throat, tongue, lips, eyes, hands, feet or ankles.