Well, yes, vitamin e can be helpful to puffy eyes, so you can just have a try. Generally speaking, there are many reasons which can cause puffy eyes, including allergies, irritants, chemicals, depression. And the skin of the eyelids is the thinnest in the body. For this reason any swelling underneath the lids or discoloration may be quite obvious. In that way, it will just cause inflammation and swelling, and finally leading to the puffy eyes. At this moment, you can just try some warm compresses with hot cloth, which can relieve your symptoms. Also, vitamin e is a powerful antioxidant that can help treat eye puffiness when it results from irritation. So just have a try.