Normally, the sclera part should be white. Tiredness might make people lose the brightness of eyes, full with bloodshots, yet the sclera still remains white in this case. People might get the yellowish deposit on sclera for collagen fiber degeneration, but it is only spot instead of whole yellow eyes. If your eyes are yellow, the culprit should be the jaundice. It is due to the bilirubin built up in the blood. Bilirubin is a yellowish pigment from the breakdown of old red blood cells. Normally it is processed by liver and stay in bile through intestine and finally excreted out in feces. If bilirubin got built up in blood, it is a sign that there is something wrong with your liver. You should go to hospital and have your blood tested as soon as possible. If leave it untreated, it would be lethal finally. I once got jaundice when I was a little kid. I got my skin as well as my eyes tinged yellow. It is a hazardous disease that I had spent totally one month in hospital to get recovered.