Prednisone is mainly used to treat various disorders, most of which is allergic reaction, for example skin conditions, asthma, and arthritis. It can be used as treatment for cancer and blood disorders. It can help reduce irritation, inflammation and swelling. It is widely used for its good function, yet side effects always come with benefits. The very common feeling of taking this medicine, you might get feelings like increasing appetite, indigestion, nervous and restless. There are some other less common or rare side effects that you might get, such as changes in pigmentation, dizziness, redness of faces, hiccups, increased sweating, feeling of spin, decreased or blurred vision, frequent urination, increased thirst, depression and confusion and so on. But it is not people taking this medication will go through all the side effects. They don't happen to everyone. You should let your doctor know what is happening to you. The doctor will balance the benefits versus side effects and decide what drugs he/she should prescribe for you. Don't worry too much.