Of course, you can't. Contact solution contains many chemical substances which are easy to cause chemical reflection if you drop them in eyes without taking off contact lenses. Commonly you feel eye dryness in that your contact lenses are in poor quality, or you have been working in a long time with wearing contact lenses. When you feel tired and fatigue, your eyes also feel uncomfortable. At this moment, eyes will produce abnormal liquids, even no any liquids. Then you may get eye dryness. Your contact lenses will absorb water in any time. And stock contact lenses in box with solution is good and right to protect them because there is no any chemical things that solution box contains. While eyes have these chemical substances indeed. So if you get eye dry when wearing contact lenses, please go to a eye care center to buy the special drops.