Now,it will not. Over-the-counter eye drops can be helpful for people whose eyes are dry, irritated, or red. But it's important to use the right eye drops in the right way to get the relief you seek and to prevent eye infections.All of these drops have a preservative in them that reduces the risk of infection,The most common way people contaminate a bottle of eye drops is by touching the lashes with the dropper tip. The bacteria can get into the bottle, but the preservative will reduce the risk of getting an infection.If you worry about using eye drops over the long term, rest assured that it%u2019s safe %u2014 as long as you follow a few basic rules.Firstly, you need to determine what kind of eye drops you need. Second, learn how to use eye drops. Third, keep an eye on expiration date. Four, know when to call a doctor.