It can roughly be divided into two types. For a class of non infiltrative ophthalmopathy, it mainly caused by sympathetic stimulation extraocular muscles and muscle of upper eyelid. Another kind is infiltrative ophthalmopathy, showed an orbital and retrobulbar tissue volume increase, lymphocytic infiltration, edema and exophthalmos. And in Graves patients, the prevalence of open-angle glaucoma, normal tension glaucoma and ocular hypertension were higher than in the general population prevalence rate, should cause people attention, close follow-up observation, so as to prevent damage to the optic nerve.