Well, yes, smoking can lead to dilated pupils. And there are many people who suffer from the symptom because of smoking. First, you should know that dilate pupils are often caused by high blood pressure. So if you keep smoking, your blood pressure can be very high, it can affect your eyes, and then lead to dilate pupils. So in my opinion, you should quit smoking. Also, hyperventilation, muscle tensions, which are the most common causes to dilated pupils. By the way, smoking can not only affect your eyes, but also, it can damage your body organ, and then do harm to your health. So just give up it.