Yes, hemorrhoid cream are considered to treat wrinkles. Although the cream is made for reduce the hemorrhoid. But it make sense to remove wrinkles of the skin on the face. However, there are different type of hemorrhoid cream right now. Some of them can't help reduce wrinkles. So, you shall consider twice before you buy. As far as i know, hemorrhoid cream label with "Canadian Preparation H with Bio-Dyne" may help reduce wrinkles. If it label shows "phenylephrine 0.25%" in ingredient, you'd better not use it since they are not the original type. Hope this can help you.