Yes,kind of.One can get yellow eyes for excessive tiredness.Do you also feel your eyes itchy,painful and dry?As far as I know,these symptoms usually come along with yellow eyes.In this case,I have some remedies for you. You have to know that if your yellow eyes are caused by fatigue,your eyes must be really dry.Why not give your eyes a regular break?Use some warm and purified water to soothe your eyes,which can help hydrate your eyes.And do eye exercise as often as you can,and this is also good for improving your eyesight.If you still feel worried,you had better go to the doctor to get your eyes a full check.Follow the doctor's instructions and you will recover very soon.