Yes, it is quite normal for eyes to twitch if you feel fatigue. When you overuse your eyes or feel uncomfortable, the muscles around the eyes may sometimes spontaneously twitch, thus making your eyes twitch. This is because that when you are using your eyes too much, the muscles and the nueromechanism of the eyes cannot get enough rest and become too active. Then the nueromechanism in the brain that are responsible for regulating actions will become overactive too, making the blink reflex unusually excited, thus the eyes twitch under the control of this. If your eyes often twitch, then you should do regular eye exercises and allow your eyes to have enough rest during and after working or reading. Use eye drops that are suitable for eye fatigue, and put foods containing vitamin A which is good for eyes into your daily diet.
