It's normal to have allergic reaction to glasses. If you feel your reaction is very severe, you'd better give up your new glasses. If you have a sensitivity to inexpensive jewelry or certain types of metal, you may need to wear a hypoallergenic frame. Nickel alloy is a common material in eyeglass frames. Even if a frame looks silver or gold, it could contain nickel, a common allergen. Stainless steel and titanium are also popular materials for frames and do not usually cause allergic reactions. However, some titanium frames contain palladium, which may cause skin problems. For allergy sufferers, finding the right frame material often requires trying a few. Plastic frames contain a combination of materials, and it may be difficult to determine the exact composition. Most plastic glasses are made of zyl or propionate but contain other materials, such as nylon, carbon, polycarbonate, optyl and polyamide. Optyl, nylon and propionate frame material are usually safe choices if you are sensitive to plastics. Your eye care provider can help determine the material content of plastic frames and find one that is hypoallergenic.